Female rats eating high fat chow acquire methamphetamine self‐administration faster than rats eating standard chow
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منابع مشابه
Haloperidol and rimonabant increase delay discounting in rats fed high-fat and standard-chow diets.
The dopamine and endocannabinoid neurotransmitter systems have been implicated in delay discounting, a measure of impulsive choice, and obesity. The current study was designed to determine the extent to which haloperidol and rimonabant affected delay discounting in rats fed standard-chow and high-fat diets. Sprague-Dawley rats were allowed to free-feed under a high-fat diet (4.73 kcal/g) or a s...
متن کاملKetogenic versus Western and standard chow diets favorably alters fat deposition and serum biomarkers in rats
Methods Male Sprague-Dawley rats (~9-10 weeks of age) were provided isocaloric amounts of either a KD (5.2 kcal/g, 20.2% protein, 10.3% carbohydrate, 69.5% fat; n = 50), WD (4.5 kcal/g, 15.2% protein, 42.7% carbohydrate, 42.0% fat; n = 66), or StdChow (3.1 kcal/g, 24.0% protein, 58.0% carbohydrate, 18.0% fat n = 10) for 6 weeks with daily food intake and body weights recorded. After the animals...
متن کاملEating High Fat Chow Decreases Dopamine Clearance in Adolescent and Adult Male Rats but Selectively Enhances the Locomotor Stimulating Effects of Cocaine in Adolescents
BACKGROUND Feeding conditions can influence dopamine neurotransmission and impact behavioral and neurochemical effects of drugs acting on dopamine systems. This study examined whether eating high fat chow alters the locomotor effects of cocaine and dopamine transporter activity in adolescent (postnatal day 25) and adult (postnatal day 75) male Sprague-Dawley rats. METHODS Dose-response curves...
متن کاملChanging standard chow diet promotes vascular NOS dysfunction in Dahl S rats.
We hypothesized that vascular nitric oxide synthase (NOS) function and expression is differentially regulated in adult Dahl salt-sensitive rats maintained on Teklad or American Institutes of Nutrition (AIN)-76A standard chow diets from 3 to 16 wk old. At 16 wk old, acetylcholine (ACh)-mediated vasorelaxation and phenylephrine (PE)-mediated vasoconstriction in the presence and absence of NOS inh...
متن کاملFat Preference: a novel model of eating behavior in rats.
Obesity is a growing problem in the United States of America, with more than a third of the population classified as obese. One factor contributing to this multifactorial disorder is the consumption of a high fat diet, a behavior that has been shown to increase both caloric intake and body fat content. However, the elements regulating preference for high fat food over other foods remain underst...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2019
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.2019.33.1_supplement.664.3